Yūta Hoshiya enters Ayana Academy, a school focusing on show business activities, specifically music. The academy has a group of the three students with the highest grades in the musical department, and they are known as the Kao Kai (Cherry Blossom Flower Association). This organization stands at the top of the pecking order within the academy. The shortcut to entering the musical department is to enter the Star Frame class, which is directly taught by the members, and to be recognized by them. Unfortunately, due to their own problems, students Tōru, Kaito, Shō, Shū, and Yūta are all struggling to even remain candidates for the musical department. By a stroke of luck, however, the five are spotted by Kao Kai member Ōtori, and they pique his interest.

The story involves a group of high school students at Ayana Academy, a school with music as its main focus. A trio of students called Hanasakura-kai, designate from the most talented of the music department. To get in, individuals must enter through a Star Frame class.

The series tells the story of Yuuta Hoshiya, Tooru Nayuki, Kaito Tsukikage, Shou Tengeiji, and Shuu Kuga as they aim for a position in the musical department after being spotted by Ootori, one of the Hanasakura-kai members.